Ultramer¢ç RNA Oligo ¿Ã¸®°í ÇÕ¼º ¼ºñ½ºIDT´Â ³ôÀº Ç°ÁúÀÇ ±ä RNA oligo(~ÃÖ´ë 120mer)¸¦ ÇÕ¼ºÇϱâ À§ÇØ ÃÖÀûÈµÈ ±â¼ú·ÂÀ¸·Î Ultramers¢ç RNA oligonucleotide¸¦ Á¦°øÇÕ´Ï´Ù. ÀÌ single stranded custom RNA´Â ´ÙÀ½ÀÇ RNA°ü·Ã ´Ù¾çÇÑ applications¿¡ Çâ»óµÈ specificity¿Í performance¸¦ Á¦°øÇÒ ¼ö ÀÖ½À´Ï´Ù.
Ultramers¢ç RNA´Â ÁÖ¹® ÈÄ ¾à 7-10ÀÏ ÈÄ¿¡ desalting °úÁ¤À¸·Î ºÒ¼ø¹°À» Á¦°ÅÇÑ µÚ¿¡ 4 nmol, 20 nmol ¶Ç´Â 80 nmol·Î Á¤·®µÈ ´ÙÀ½ °ÇÁ¶µÈ »óÅ·Πtube¿¡ ³Ö¾îÁ® ¹è¼ÛµË´Ï´Ù. Á¦Ç°°ú ÇÔ²² ESI mass spectrometry QC ÀڷḦ ÇÔ²² ¹ÞÀ» ¼ö ÀÖ½À´Ï´Ù.
IDT´Â RNA ÇÕ¼ºÀÇ
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ÀÚüÀÇ solid supportÀÇ pairingÀ¸·Î
ÃÖÀûÈµÈ RNA ÇÕ¼º ±â¼úÀ» º¸À¯ÇÏ°í ÀÖ½À´Ï´Ù. IDTÀÇ R&D ÆÀÀº ¼º°øÀûÀ¸·Î ±ä RNAÀÇ ÇÕ¼ºÀ» À§ÇØ RNA oligoÀÇ coupling efficiency¸¦ 99.0-99.3%±îÁö Çâ»óÇÏ¿© Ultramers¢ç RNA·Î Á¦°øÇÕ´Ï´Ù. Product Specifications:
Ultramer¢ç RNA ¼ºñ½º¿¡ °¡´ÉÇÑ Modificaions.
Figure 1. The general relationship between percentage of full-length product, coupling efficiency, and oligo length. Coupling efficiency becomes increasingly important with increased oligo length. In long oligos, small changes in coupling efficiency have dramatic effects on full-length yield. The graphs depicts the difference in full-length product for coupling efficiencies of 99.0–99.3% (dark blue) and 98.0–98.5% (light blue) Figure 2B. QC data demonstrates high purity of a 120mer Ultramer¢ç RNA Oligo. The measured molecular weight of the oligo is within 0.01% of its expected molecular weight, which is determined by the specific oligo sequence. Data generated from ESI-MS instruments at IDT.
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